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Rhodes, Christopher

One or more keywords matched the following items that are connected to Rhodes, Christopher

Item Type	Name
Concept	Signal Transduction
Academic Article	Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.
Academic Article	A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.
Academic Article	Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).
Academic Article	Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.
Academic Article	Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells.
Academic Article	Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation.
Academic Article	Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
Academic Article	Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?
Academic Article	Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
Academic Article	A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.
Academic Article	Type 2 diabetes-a matter of beta-cell life and death?
Academic Article	Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells.
Academic Article	Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
Academic Article	Impact of defined matrix interactions on insulin production by cultured human beta-cells: effect on insulin content, secretion, and gene transcription.
Academic Article	Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.
Academic Article	Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt?
Academic Article	Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression.
Academic Article	Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.
Academic Article	Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation.
Academic Article	Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.
Academic Article	Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts.
Academic Article	Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.
Academic Article	Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
Academic Article	Molecular insights into insulin action and secretion.
Academic Article	Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).
Academic Article	IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells.
Academic Article	Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve.
Academic Article	Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1.
Academic Article	IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication.
Academic Article	Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells.
Academic Article	Intracellular signalling. Key enzyme in leptin-induced anorexia.
Academic Article	A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake.
Academic Article	Direct autocrine action of insulin on ß-cells: does it make physiological sense?
Academic Article	ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
Academic Article	ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
Academic Article	a1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders.
Academic Article	RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.
Academic Article	BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFß-TAK1-MAPK pathways in PAH.
Academic Article	Leptin action in the forebrain regulates the hindbrain response to satiety signals.
Academic Article	Free radicals, metals and antioxidants in oxidative stress-induced cancer.
Academic Article	Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.
Academic Article	Redox- and non-redox-metal-induced formation of free radicals and their role in human disease.
Academic Article	The dynamic plasticity of insulin production in ß-cells.
Academic Article	Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
Academic Article	Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
Academic Article	Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production.
Academic Article	Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.
Grant	Mitogenic Signal Transduction in Pancreatic Beta-Cells

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Signal Transductions